Publications

2027

2026

#24 Weyand, I., Arenz, L.A., Reddy, L.R., Hopp, M.-T. (2026) Attenuation of fibrinolysis through heme binding to the serine protease plasmin. Int. J. Biol. Macromol. 385: 154990.

#23 Kröner, L., Meier, J., Hopp, M.-T. (2026) Bioactive Peptides from Caudate Amphibians: Synthesis and Assessment of Antioxidant and Antimicrobial Activities. J. Nat. Prod. 89(5): 1426–1439.

#22 Lindemann, P., Hopp, M.-T. (2026) Human protein Z as the second known heme-binding protein from the endogenous blood coagulation inhibitor system. ChemBioChem. 27(1): e202500636.

#21 Hopp, M.-T. (2026) Wirkstoffreich aber unterschätzt: Heimische Amphibien als Quelle bioaktiver Peptide. Chem. unserer Zeit. 60(2): 88–93.

2024

#20 Hopp, M.-T., Vaidya, S.M., Grimmig, K.M., Strudthoff, L.J., Clauser, J.C., Yuan, X., Singh, S., Müller, J., Oldenburg, J., Hamza, I., Imhof, D. (2024) Quantitative analysis of heme and hemoglobin for the detection of intravascular hemolysis. Anal. Chim. Acta, DOI: 10.1016/j.aca.2024.342766

#19 Kröner, L., Lötters, S., Hopp, M.-T. (2024) Insights into caudate amphibian skin secretions with a focus on the chemistry and bioactivity of derived peptides. Biol. Chem. 405(9-10): 641–660.

#18 Hopp, M.-T.*, Ugurlar, D., Pezeshkpoor, B., Biswas, A., Ramoji, A., Neugebauer, U., Oldenburg, J., Imhof, D. (2024) In-depth structure-function profiling of the complex formation between coagulation factor VIII and heme. Thromb. Res. 237: 184-195.

#17 Hopp, M.-T., Holze, J., Lauber, F., Holtkamp, L., Rathod, D. C., Miteva, M. A., Prestes, E. B., Geyer, M., Manoury, B., Merle, N., Roumenina, L., Bozza, M. T., Weindl, G., Imhof, D. (2024) Insights into the molecular basis and mechanism of heme-triggered TLR4 signaling: The role of heme-binding motifs in TLR4 and MD2.  Immunology 7(2), 181-197.

2023

#16 Alibayov, B., Scasny, A., Vidal, A.G.P., Murin, L., Wong, S.M., Edwards, K., Eichembaun, Z., Punshon, T., Jackson, B., Hopp, M.-T., McDaniel, L.S., Akerley, B.J., Imhof, D., Vidal, J.E. (2023) Oxidation of hemoglobin in the lung parenchyma facilitates the differentiation of pneumococci into encapsulated bacteria. BioRxiv, doi: 10.1101/2023.11.14.567109. 

#15 Hopp, M.-T., Imhof, D. (2023) Häm-Interaktionen an der Schnittstelle zwischen SARS-CoV-2 und Wirtszelle. BIOspektrum 29(6), 625-628.

#14 Rathod, D. C., Vaidya, S. M., Hopp, M.-T., Kühl, T., Imhof, D. (2023) Shapes and patterns of heme-binding motifs in mammalian heme-binding proteins. Biomolecules 13(7), 1031.

2022

#13 Mubeen, S., Domingo-Fernandez, D., Díaz del Ser, S., Solanki, D., Kodamullil, A. T., Hofmann-Apitius, M., Hopp, M.-T.*, Imhof, D.* (2022) Exploring the complex network of heme-triggered effects on the blood coagulation system. J. Clin. Med. 11(19), 5975.

#12 Hopp, M.-T., Rathod, D. C., Imhof, D. (2022) Host and viral proteins involved in SARS-CoV-2 infection differentially bind heme. Protein Sci. 31(11), e4451.

#11 Hopp, M.-T., Rathod, D. C., Winn, K. H., Ambast, S., Imhof, D. (2022) Novel insights into heme binding to hemoglobin. Biol. Chem. 403(11-12), 1055-1066.

#10 Hopp, M.-T., Paul George, A. A., Ramoji, A., Detzel, M. S., Pepanian, A., Neugebauer, U., Imhof, D. (2022) A model peptide reveals insights into the interaction of human hemopexin with heme. Int. J. Pept. Res. Ther. 28, 129.

2021

#9 Hopp, M.-T., Alhanafi, N., Paul George, A. A., Hamedani, N. S., Biswas, A., Oldenburg, J., Pötzsch, B., Imhof, D. (2021) Molecular insights and functional consequences of the interaction of heme with activated protein C. Antioxid. Redox. Signal. 34(1), 32-48.

#8 Hopp, M.-T., Imhof, D. (2021) Linking labile heme with thrombosis. J. Clin. Med. 10(3), 427.

#7 Hopp, M.-T., Domingo-Fernández, D., Gadiya, Y., Detzel, M. S., Graf, R., Schmalohr, B. F., Graf, R., Kodamullil, A. T., Imhof, D., Hofmann-Apitius, M. (2021) Linking COVID-19 and heme-driven pathophysiologies: A combined computational-experimental approach. Biomolecules 11(5), 644.

#6 Detzel, M. S., Schmalohr, B. F., Steinbock, F., Hopp, M.-T., Ramoji, A., Paul George, A. A., Neugebauer, U., Imhof, D. (2021) Revisiting the interaction of heme with hemopexin. Biol. Chem. 402(6), 675-691.

2020

#5 Humayun, F., Domingo-Fernández, D., Paul George, A. A., Hopp, M.-T., Syllwasschy, B. F., Detzel, M. S., Hoyt, C. T., Hofmann-Apitius, M., Imhof, D. (2020) A computational approach for mapping heme biology in the context of hemolytic disorders. Front. Bioeng. Biotechnol. 8, 74.

#4 Hopp, M.-T., Schmalohr, B. F., Kühl, T., Detzel, M. S., Wißbrock, A., Imhof, D. (2020) Heme determination and quantification methods and their suitability for practical applications and every-day use. Anal. Chem. 92(14), 9429-9440.

#3 Syllwasschy, B. F., Beck, M. S., Druzeta, I., Hopp, M.-T., Ramoji, A., Neugebauer, U., Nozinovic, S., Menche, D., Willbold, D., Ohlenschläger, O., Kühl, T., Imhof, D. (2020) High-affinity binding and catalytic activity of His/Tyr-based sequences: Extending heme-regulatory motifs beyond CP. Biochim. Biophys. Acta – Gen. Subj. 1864(7), 129603.

#2 Paul George, A. A., Lacerda, M., Syllwasschy, B. F., Hopp, M.-T., Wißbrock, A., Imhof, D. (2020) HeMoQuest: A webserver for qualitative prediction of transient heme binding to protein motifs. BMC Bioinformatics 21(1), 124.

2011

#1 Hopp, A.-K., Hopp, M.-T., Krajewski, F., Hopp, K., Blecker, J. (2011) Bekannte Fundorte des Tuber aestivum in Deutschland, sowie Möglichkeiten ihres Anbaus und Vorschläge zu Verbreitungsmöglichkeiten. Z. Mykol. 77(2), 88-102.